False! While becoming a donor does require some time to fill out the paperwork and swab your cheek, it is much smaller of a time commitment than you think. Before you donate, there are several steps to make sure you are the best donor for the patient. These steps include an information session to provide resources to help you make your decision, as well as appointments for additional blood tests and a physical exam. The time needed for the actual donation depends on the donation procedure. On average, the entire process can take 30 to 40 hours, including travel time, over 4 to 6 weeks. Marrow and PBSC donation require about the same total time commitment.